National Centre for Pharmacoeconomics

National Centre for
Pharmacoeconomics

NCPE Ireland

Director:
Prof. Michael Barry MB, FRCPI, PhD
Prof. Michael Barry is a Consultant Clinical Pharmacologist and Head of the Department of Pharmacology & Therapeutics at the University of Dublin, Trinity College. He is the clinical director of the National Centre for Pharmacoeconomics which conducts pharmacoeconomic evaluations on medicines prior to reimbursement under the Community Drugs schemes in Ireland. He is Past-President (2010-2011) of the International Society for Pharmacoeconomics and Outcomes Research (ISPOR). He was a board member of the Health Information and Quality Authority (HIQA) and is a member of a number of National Committees on pricing and reimbursement of medicines. Prof. Barry chairs the New Drugs Committee and the Medication Safety Committee at St. James’s Hospital, Dublin. In 2013 he was appointed as Clinical Lead for the new HSE Medicines Management Programme. He is a fellow of the Royal College of Physicians in Ireland and is a specialty trainer for Pharmacology & Therapeutics. His research areas include the cost-effectiveness of high cost drugs including chemotherapeutic agents and biologic drugs, pricing and reimbursement and performance based risk sharing schemes. He has published widely on the cost-effectiveness of medicines in the Irish healthcare setting.
Email: mbarry@stjames.ie
Deputy Head of NCPE:
Dr. Lesley Tilson BSc (Hons) Pharm, PhD
Dr. Lesley Tilson is Chief I Pharmacist at the National Centre for Pharmacoeconomics and is a graduate of the University of Brighton. She trained in the Chelsea and Westminster hospital, London and then worked as a resident pharmacist at the Oxford Radcliffe Hospitals NHS Trust. During this time she completed a Diploma in Clinical Pharmacy with Cardiff University. Lesley worked as a senior clinical pharmacist at St James’s Hospital Dublin, on the intensive care unit and cardiac surgery ward. She has a PhD from the Department of Pharmacology and Therapeutics, Trinity College Dublin (2002-2005) and a Diploma in Statistics from Trinity College Dublin (2003-2004). She is a lecturer in pharmacoeconomics to undergraduate and postgraduate pharmacy students. Research interests include: Economic evaluation of pharmaceuticals in the Irish setting, pharmaceutical pricing and reimbursement strategies, policies to promote generic markets, international pharmaceutical pricing, analysis of drug utilisation and expenditure trends. She received the ISPOR Bernie O’Brien New Investigator Award in May 2011.
Email: ltilson@stjames.ie
Current staff include:
Dr. Roisin Adams, MPharm, MSc., PhD
Dr. Roisin Adams is Head of HTA Strategy and External engagement for the NCPE. Dr. Adams led the HTA team for a number of years before being seconded to the HSE to lead a new unit tasked with overseeing and managing high cost drugs in acute hospitals.  Dr. Adams co- chairs the HTA domain of the BeNeLuxA initiative and oversees the EUNetHTA work of the NCPE. She has been awarded a number of grants from the Health Research Board to examine health preferences in Ireland, the most recent examines patient preferences in HTA. Her areas of interest  include methods for preference elicitation, combining different data for evidence synthesis and reimbursement mechanisms for high cost drugs.  She has held advisory positions for Department of Health, the Health Information and Quality Authority and policy direction at EU level.
Email: radams@stjames.ie
Prof. Kathleen Bennett BSc, PhD (Statistics)
Professor Kathleen Bennett is Associate Professor in Biostatistics at the RCSI (Royal College of Surgeons in Ireland) Division of Population Health Sciences, and a Health Research Board (HRB) Research Leader. Professor Bennett leads a research team undertaking a programme of research titled “Statistical epidemiology in Population Health and Health Services Research: Quality and Patient Safety in Medicines”. Professor Bennett has over 25 years’ experience of undertaking medical research. After completing her BSc in mathematics and statistics at Southampton University, UK she spent 2 years working as a clinical trials statistician in the Pharmaceutical Industry before returning to Southampton to complete a PhD. She was employed as an epidemiologist/statistician in the Department of Pharmacology and Therapeutics, Trinity College Dublin for many years and retains a part-time position in the Department. Professor Bennett is an advisor to the National Centre for Pharmacoeconomics on pharmacoepidemiology and statistics.
Email: kathleenebennett@rcsi.ie
  Niamh Carey BSc (Pharm), MPharm, MSc (Health Economics)
Niamh Carey is a Research Fellow at the National Centre for Pharmacoeconomics. She is a graduate of the School of Pharmacy, Trinity College Dublin and also holds a Masters of Pharmacy degree from the Royal College of Surgeons in Ireland. Her previous experience lies primarily in community pharmacy where she worked following completion of her MPharm studies.  During this time, she obtained a Masters in Health Economics from the National University of Ireland Galway. Niamh is currently undertaking a PhD at the NCPE, focusing on the area of health technology assessment.
Email: ncarey@stjames.ie
Owen Cassidy BA (Mod.), MSc (Ind.)
Owen Cassidy is undertaking a PhD at the NCPE, focusing on statistical methodologies for use in HTA. He is a graduate of Management Science and Information Systems (MSISS) at Trinity College Dublin, during which he completed a final year project entitled “Development of cost-effectiveness models in R” for the NCPE which was jointly awarded the IBM David Dier Memorial Prize. He was awarded a research grant from the Irish Research Council to undertake a Masters by research in partnership with an industry employer, investigating an evidence synthesis technique: Matching-Adjusted Indirect Comparisons in HTA and their implementation using R.
Email: ocassidy@stjames.ie
 

Cliona Flynn BSc, (Hons) Human Nutrition
Cliona is an information specialist at the National Centre for Pharmacoeconomics. She graduated from Ulster University with a BSc Hons in Human Nutrition and a Diploma in Industrial Studies. She is currently completing her MSc in Epidemiology with the London School of Hygiene & Tropical Medicine. Prior to her appointment at the NCPE, Cliona worked with the Northern Ireland Statistics & Research Agency producing official statistics and social research and with the Calgary Health Region on a large systematic review examining best practice for the prevention and treatment of childhood obesity. Other work included research with Ulster University, University College Dublin and the Food Safety Authority of Ireland.
Email: cliflynn@stjames.ie 
Dr. Emer Fogarty BSc Pharm, Dip (Stat), MSc, PhD
Emer Fogarty is acting Chief II Pharmacist and a member of the economic review group at the National Centre for Pharmacoeconomics. She graduated from Trinity College, Dublin in 2004 and completed an MSc in Clinical Pharmacy with University College, Cork. Formerly employed as a clinical pharmacist in St. James’s Hospital, Emer worked in numerous clinical pharmacy specialities including general medicine, oncology, and infectious diseases. She completed a PhD examining the cost-effectiveness of treatments for multiple sclerosis, and her research interests are comparative effectiveness and health economic modelling.
Email: efogarty@stjames.ie
Niamh Geraghty
Niamh is the office administrator for the National Centre for Pharmacoeconomics. She completed a computer/receptionist course in Crumlin College of Business and Technical studies in 1989. Prior to starting in St. James’s Hospital in 1996 Niamh had been working for a private orthodontist for six years. Since joining St. James’s Hospital she has worked in various different departments including the Central Pathology Laboratory and Personnel (Human Resources). She also spent time working with the National Medicines Information Centre before joining the National Centre for Pharmacoeconomics (NCPE) in 2000.Email: barrysec@stjames.ie
Claire Gorry
Claire Gorry is a graduate of the School of Pharmacy, Trinity College Dublin. She completed a community pharmacy pre-registration placement and has since gained experience in community, hospital and industry roles. Most recently she has worked as haematology/oncology clinical trials pharmacist in St James hospital. Claire has completed a post graduate diploma in Clinical Pharmacy from Queen’s University Belfast and a diploma in Health Economics from University College Dublin. Claire is currently undertaking a PhD in the NCPE, researching the cost effectiveness of treatments for metastatic melanoma.
Email: CGorry@stjames.ie
Marie Harte BSc (Hons), MPH
Marie Harte is an information specialist at the National Centre for Pharmacoeconomics. She graduated from Manchester Metropolitan University with a BSc Hons in Human Nutrition and subsequently completed the Master of Public Health (MPH) programme at University College Dublin. Marie previously worked as a senior horizon analyst at the Horizon Scanning Research and Intelligence Centre at the University of Birmingham. Marie has also worked at the Irish Research Council and the Health Research Board.
Email: mharte@stjames.ie
Conor Hickey BA, MSc
Conor Hickey is a Statistician at the National Centre for Pharmacoeconomics. Conor is a Theoretical Physics graduate of Trinity College Dublin, having received his degree in 2016. Subsequently Conor received a scholarship to attend Imperial College London where he completed a M.Sc. in Epidemiology. The focus of Conor’s research at Imperial was investigating and comparing commonly used distribution sampling methods in infectious disease modelling. As part of his research Conor developed, using the R programming language, a deterministic compartmental model of HIV transmission in the Senegalese setting.
Email: cohickey@stjames.ie
Dr. Felicity Lamrock
Dr. Felicity Lamrock is a Lecturer in Data Analytics at Queen’s University Belfast. She was previously a full-time statistician at the National Centre for Pharmacoeconomics before taking up her current post. Felicity completed her PhD in Medical Statistics from Queen’s University Belfast in 2016 which involved developing new statistical methodology and creating a model to test the cost-effectiveness of a panel of novel biomarkers to prevent cardiovascular disease. Felicity is also an Adjunct Researcher at the Institute for Public Health, Medical Decision Making and HTA at the University for Health Sciences Informatics and Technology (UMIT), Austria. Felicity is now a statistical advisor to the National Centre for Pharmacoeconomics on statistical methodology for Health Technology Assessment. Research interests include combining the areas of statistics, decision modelling, pharmacoeconomics and data analytics. Her current work involves exploring how Northern Ireland could benefit from more decision modelling/pharmacoeocnomic assessment.
Email:f.lamrock@qub.ac.uk
Dr. Joy Leahy
Dr Joy Leahy is a statistician at the National Centre for Pharmacoeconomics. She is a graduate of Mathematics and Statistics from University College Cork and holds a PhD in statistics from Trinity College Dublin (TCD). Her research interests include Bayesian methods for evidence synthesis and Network Meta-Analysis (NMA), with particular focus on the appropriate use of lesser quality evidence. She has worked on applications of these methods to disease networks such as Hepatitis C, melanoma and multiple myeloma.  She was previously employed as a research assistant in the National University of Ireland, Galway, where she worked on an NMA comparing pharmaceutical and behavioural interventions for hypertension. She is a statistical ambassador with the Royal Statistical Society and was the 2017/2018 TCD student chapter president for the International Society for Pharmacoeconomics and Outcomes Research.
Orla Maguire (MPharm, MSc)
Orla is a pharmacist and Health Technology Assessor at the National Centre for Pharmacoeconomics. She graduated from Queens University Belfast and subsequently completed an M.Sc. in Hospital Pharmacy from Trinity College, Dublin. Prior to her appointment to the NCPE, Orla was employed as senior clinical pharmacist in St James’s Hospital, Dublin.  During that time, she worked in various clinical specialities and also occupied the roles of procurement pharmacist, editor to the SJH Prescriber’s Guide and secretary to the SJH New Drugs Committee. Her most extensive experience is within the critical care setting where she occupied the role of ICU pharmacist for more than 5 years.
Email: omaguire@stjames.ie
Dr. David McConnell, BA (Mod), PhD
Dr David McConnell is a statistician at the National Centre for Pharmacoeconomics. David studied at Trinity College Dublin, completing his BA in mathematics in 2010 and his PhD in mathematical analysis in 2015.  He subsequently held lectureships at the University of Glasgow and Cardiff University.  At Cardiff he ran the Mathematics Support Service, a university-wide centre providing mathematical and statistical assistance to students and researchers, and was a founding member of the mathematics education research group.  He is a Fellow of the Higher Education Academy.  His role at the NCPE involves evaluating the statistical analysis and modelling methodology in health technology assessment submissions, as well conducting research and developing guidelines for best practices in these areas.
Email: dmcconnell@stjames.ie
 

Dr. Laura McCullagh BSc (Hons) Pharm, Dip., PhD
Dr Laura McCullagh is Head of Research, a Chief I Pharmacist  and a member of the Senior Management Team within the NCPE. Dr McCullagh is a lead health technology assessor. Roles include various teaching and research commitments and the supervising of PhD and post-doctoral research within the department. Previous roles have included Associate Professor of Pharmacoeconomics & Health Technology Assessment, Trinity College Dublin (2016-2018), HRB Research Fellow, Chief II Pharmacist (St James’s Hospital, Dublin) and Senior Medicines Information Pharmacist (Oxford Radcliffe Trust, UK). Dr McCullagh holds a PhD (Trinity College Dublin) for her research which focused on Health Technology Assessment within the Irish Healthcare Setting. Dr McCullagh is a graduate of the Sunderland School of Pharmacy and  she completed her diploma in hospital pharmacy at De Monfort University, Leicester. Research interests include pharmacoeconomic evaluations, value of information analysis and survival analysis.
Email: mcculllm@tcd.ie
Caitríona Ní Choitir (MPharm, MSc)
Caitríona Ní Choitir is a Senior Research Fellow at the National Centre for Pharmacoeconomics. A member of the NCPE review group team, Caitríona is also the national clinical data manager for the Irish Hepatitis C Treatment Registry. She holds a Masters in Pharmacy degree from the Robert Gordon University of Aberdeen and an MSc in International Health Policy and Health Economics from the London School of Economics and Political Science. Prior to joining the NCPE, Caitríona worked as a data analytics and service improvement consultant in the NHS and as a senior health economics and outcomes research consultant in the pharmaceutical industry. Caitríona is presently a member of the Council of Clinical Information Officers, eHealth Ireland. Research interests include; pharmaceutical economics and policy, outcomes research and methods for the economic evaluation of technologies and health care.
Email: CNiChoitir@stjames.ie
Joan O’Callaghan BSc Pharm, MSc, MRes
Joan O’Callaghan is a Health Technology Assessor at the National Centre for Pharmacoeconomics.  She is a graduate of the School of Pharmacy, Trinity College Dublin. Upon completion of her degree she completed her pre-registration training at St. James’s Hospital, Dublin.  Joan subsequently worked as a pharmacist in the hospital and community settings.  Most recently she has worked at the Health Products Regulatory Authority (HPRA) as both a Pharmaceutical Assessor and a Research Scientist.  Her research in the HPRA focused on the area of biosimilar medicines.  Joan holds a Masters by Research from University College Cork and a MSc. in Biopharmaceutical Science from IT Sligo.
Email:jocallaghan@stjames.ie
Joanne O’Connor MSc
Joanne is a health economist at the National Centre for Pharmacoeconomics. Prior to this role, Joanne was employed as a health economist with the Centre for Reviews and Dissemination at the University of York, contributing to health economic components of projects commissioned under the NIHR Technology Assessment Reviews programme for NICE. In addition, this role included undertaking critical appraisal of published economic evaluations and undertaking projects commissioned by NIHR, in the areas of neurology, rheumatology and medical devices. Joanne has previously worked at Newcastle University, working on trial-based economic evaluations and preference elicitation exercises to inform economic models. Joanne is a graduate of University College Cork (UCC), where she completed an MSc in Health Economics. She also completed her BSc Finance at UCC. Joanne’s research interests include health technology assessment methods and review methods to inform economic models.
Email: jooconnor@stjames.ie
Helen O’Donnell BSc Pharm, MPharm, MSc (Health Economics)
Helen O’Donnell is a research pharmacist at the National Centre for Pharmacoeconomics. Helen is a graduate of Trinity College Dublin where she was elected a scholar. She completed her MPharm studies at the Royal College of Surgeons in Ireland. After qualifying as a pharmacist in 2012, Helen worked in community pharmacy before undertaking a Masters in Health Economics in National University of Ireland Galway. She is currently undertaking a PhD examining the cost-effectiveness of lipid lowering treatments in Ireland.
Email: HODonnell@stjames.ie
Dr. Aisling O’Leary BSc Pharm, PhD
Dr. O’Leary MPSI, a graduate of the School of Pharmacy, Dublin University, Trinity College with a Ph.D in pharmaceutical chemistry, is a Chief II pharmacist in the centre. Her background is predominantly in hospital pharmacy where she worked in a variety of clinical disciplines including GUIDE, endocrinology, rheumatology and dermatology. She co-ordinated the M.Sc. in Hospital Pharmacy from 1995 to 2005 under the auspices of TCD. She retains an academic teaching role with the School of Pharmacy, RCSI where she is Programme Director of Studies of the National Pharmacy Internship Programme. She is a member of the Irish Medication Safety Network, the Hospital Pharmacists Association of Ireland and the 2012 Hospital Pharmacy Assessment Group (PSI). Since 2005 she has been involved in the appraisal of the cost-effectiveness of new technologies for the centre.
Email: aoleary@stjames.ie
Dr. Susan Spillane Phd, MPharm
Susan Spillane is a health technology assessor at NCPE. Following Susan’s undergraduate (UCC) and MSc pharmacy studies (RCSI) and a year as an intern pharmacist, St James’s Hospital, she completed a PhD in cancer pharmacoepidemiology at Trinity College Dublin. Her work leveraged linked HSE PCRS pharmacy claims data and National Cancer Registry Ireland data to examine outcomes of patients receiving commonly used medications prior to a cancer diagnosis. Susan joined the HSE Medicines Management Programme as a postdoctoral researcher in 2014 and began working also with the NCPE on drug utilisation research projects and as a health technology assessor. Between 2016 and 2019 Susan completed an MSc in public health (health economics stream) at the London School of Hygiene and Tropical Medicine and worked as a visiting research fellow at the National Cancer Institute, Maryland, US, as part of the HRB Cancer Prevention Fellowship Programme. Her ongoing research includes a range of projects using real world data to better understand national-level medicine usage patterns and clinical outcomes, particularly among patients with cancer.
Email: suspillane@stjames.ie
Dr. Lea Trela-Larsen BSc (Hons), PhD
Lea Trela-Larsen is a senior statistician at the National Centre for Pharmacoeconomics (NCPE). She completed a Mathematics BSc Hons and a PhD in Epidemiology and Statistics both at University of Bristol. She has previously worked as an analyst with the UK Government Statistical Service and as a senior research associate at University of Bristol working with National Joint Registry for England, Wales, Northern Ireland and the Isle of Man. Prior to taking up her current position Lea was a post-doctoral researcher at University of Limerick and worked with the NCPE on a project examining stakeholder requirements for real-world drug utilisation evidence.  Research interests include survival analysis, and use of administrative and secondary data.
Email:ltrela@stjames.ie
Dr. Cara Usher BSc, PhD
Dr. Cara Usher is Senior Research Fellow at the National Centre for Pharmacoeconomics. Dr. Cara Usher is Senior Research Fellow at the National Centre for Pharmacoeconomics. She holds a PhD (Pharmacology) from University College Dublin and a post-graduate diploma in Health Economics from the University of York. Overall her work has focused on evaluation of healthcare technologies, education about the evaluation process and examining the effects of reimbursement decisions through a national primary care prescription database. Her research interests include analysis of pharmaceutical policy interventions and their impact on prescribing in the community. She holds a new investigator award from the International society for pharmacoeconomics and outcomes research (ISPOR, 2008) and is a visiting research fellow at Trinity College Dublin.
Email:cusher@stjames.ie
Dr. Áine Varley MB BCh BAO (Hons), MRCPI, MSc (Health Economics)
Áine is a health technology assessor and medical doctor at the National Centre for Pharmacoeconomics. She graduated with a medical degree from University College Dublin in 2015, before working as a doctor in internal medicine for a number of years. She completed her Basic Specialist Training in General Internal Medicine through the Mater training scheme in 2018 and currently holds membership of the Royal College of Physicians of Ireland. In 2019, Áine completed an MSc in Health Economics through the National University of Ireland Galway, where she was awarded Best Overall Student. In addition to her role as a health technology assessor, she continues clinical work with the clinical pharmacology service in St James’s Hospital.
Email:avarley@stjames.ie
Prof. Cathal Walsh MA, PhD
Prof. Cathal Walsh is a Professor in Statistics at Trinity College Dublin and a HRB Research Leader in Health Decision Science. Specific areas in which he has used his expertise are in the modelling of heterogeneity using latent variable models and in combining evidence from multiple sources. He has held visiting appointments in Bayesian groups in Australia and the United States. He contributes to the statistical societies in the UK and Ireland and is currently a member of the Council of the Royal Statistical Society. He is a Statistical Editor for the Cochrane Collaboration and has served as Associate Editor for statistics journals. He is an advisor to the National Centre for Pharmacoeconomics on statistical methodology for Health Technology Assessment.
Email: Cathal.Walsh@tcd.ie
Dr. Arthur White, BA (Mod), PhD
Dr. Arthur White is a statistician at the National Centre for Pharmacoeconomics,and an Assistant Professor in the discipline of Statistics in the School of Computer Science and Statistics in Trinity College Dublin. Arthur is a Mathematics graduate of Trinity College Dublin, receiving his degree in 2009. He holds a PhD from the School of Mathematics and Statistics in University College Dublin, for research into latent variable models for multivariate and network data. This work was undertaken as a member of Clique, an SFI funded strategic research cluster. He was previously a postdoctoral researcher for the HRB funded Centre for Health Decision Science. His research interests include Bayesian methods for calibration, model selection and model averaging, and model-based clustering methods. He has worked on applications related to hepatitis C and melanoma, and investigated health service usage patterns among the Irish frail elderly population.
Email: arwhite@stjames.ie