1st Sep 10 - NCPE review of the cost-effectiveness of certolizumab pegol (Cimzia®) for the treatment of moderate to severe rheumatoid arthritis.
We do not recommend reimbursement of certolizumab pegol (Cimzia®) under the Community Drugs Schemes at the proposed price.
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15th Jul 10 - NCPE review of the cost-effectiveness of denosumab (Prolia®).
We consider denosumab a cost-effective therapy for the prevention of osteoporotic fractures in postmenopausal women in the Irish heathcare setting.
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13th Jul 10 - New template for rapid review assessment submissions from manufacturers.
Our new template for the rapid review process is to be found in the section "Pharmacoeconomic Guidelines".
13th Jul 10 - NCPE review of the cost-effectiveness of oral oxycodone/naloxone prolonged release tablet (Targin®).
We do not recommend reimbursement of oxycodone/naloxone (Targin®) under the Community Drugs Schemes at the proposed price.
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13th Jul 10 - Mifamurtide (Meptact®) for the treatment of osteosarcoma.
A formal PEA is required to demonstrate value for money prior to reimbursement.
22nd Jun 10 - Rapid review of Ofatumumab (Arzerra®) for the treatment of chronic lymphocytic leukaemia (CLL).
We believe a formal PEA will be required to demonstrate value for money prior to reimbursement.
2nd Jun 10 - NCPE review of the cost-effectiveness of golimumab (Simponi®) for the treatment of moderate to severe rheumatoid arthritis.
Following a revision in price we consider golimumab a cost-effective option for the treatment of rheumatoid arthritis in the Irish Healthcare setting.
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11th May 10 - NCPE evaluation of the cost effectiveness of golimumab (Simponi®) for the treatment of moderate to severe rheumatoid arthritis.
The reveiw group do not consider golimumab cost-effective at the submitted price.
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5th Mar 10 - Economic Evaluation of Eculizumab (Soliris®) for the treatment of paroxysmal noctural haemoglobinuria (PNH).
Alexion Pharma UK. Ltd have failed to demonstrate the cost-effectiveness of eculizumab for the treatment of PNH in the Irish healthcare setting.
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1st Feb 10 - Economic Evaluation of Prasugrel (Efient®) for the prevention of atherothrombotic events in patients with acute coronary syndrome undergoing primary or delayed percutaneous coronary intervention.
The review group consider that prasugrel, co-administered with aspirin, is cost-effective in patients with acute coronary syndrome undergoing primary or delayed percutaneous coronary intervention in the Irish healthcare setting.
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15th Jan 10 - NCPE review of Indacaterol (Onbrez®) for the treatment of COPD
It is recommended that Indacaterol (Onbrez®) should not be subjected to a PEA at this time.
15th Jan 10 - NCPE evaluation of the cost-effectiveness of the rotavirus vaccine.
NCPE completed the evaluation of the cost-effectiveness of a universal rotavirus vaccination programme in Ireland, on behalf of the National Immunisation Advisory Committee (NIAC). A summary of the main findings are available in the attached document:
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12th Jan 10 - NCPE Review of Dronedarone (Multaq®) for the treatment of current non-permanent atrial fibrillation.
It is recommended that dronedarone should not under PEA at this time.
11th Dec 09 - NCPE evaluation of agomelatine (Valdoxan®) for the treatment of major depressive disorder.
Following a revision in price application we now consider agomelatine (Valdoxan®) cost effective under the Community Drugs schemes. The product will now be added to the list of items reimbursable under the schemes.
8th Dec 09 - Cost effectiveness of Ustekinumab (Stelara®) for the treatment of moderate to severe plaque psoriasis.
We consider ustekinumab cost effective for the treatment of moderate to severe plaque psoriasis in the Irish healthcare setting.
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8th Dec 09 - NCPE review of Adenuric (Febuxostat®) a xanthine oxidase inhibitor for the treatment of gout.
It is recommended that Adenuric (Febuxostat®) should not be subjected to PEA at this time.
19th Nov 09 - NCPE review of Ranolazine (Ranexa®) a late sodium channel inhibitor for the treatment of angina pectoris.
We recommend that Ranolazine should not undergo PEA at this time.
15th Oct 09 - NCPE Review of degarelix (Firmagon®) a GnRH antagonist for the treatment of prostate cancer.
Following review it was recommended that degarelix should not be subjected to PEA at this time.
7th Oct 09 - NCPE Review of Liraglutide (Victoza®) for the treatment of adults with type 2 diabetes mellitus.
Following review it was recommended that Liraglutide should not be subjected to PEA at this time.
3rd Sep 09 - NCPE evaluation of agomelatine (Valdoxan®) for the treatment of major depressive disorder.
At the current price agomelatine (Valdoxan®) is not considered cost-effective for the treatment of major depressive episodes under the Community Drugs Schemes.
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18th Jun 09 - NCPE evaluation of sapropterin (Kuvan®) for the treatment of phenylketonuria (PKU).
Sapropterin (Kuvan®) is not a cost effective treatment for patients with phenylketonuria.
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17th Jun 09 - Health technology assessment (HTA) of a population-based colorectal cancer screening programme in Ireland.
This HTA was prepared by the National Cancer Registry Ireland, the National Centre for Pharmacoeconomics, the School for Health & Related Research, Sheffield University and Dublin City University. It is available on the HIQA website.
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16th Jun 09 - NCPE evaluation of the cost effectiveness of glucosamine sulfate (DONA®) for the treatment of osteoarthritis.
We do not believe that glucosamine sulfate (DONA®) is a cost effective therapy for the treatment of osteoarthritis in the Irish Healthcare setting.
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2nd Jun 09 - NCPE evaluation of the impact of the post-patent price cut on medicines following the 2006 IPHA-HSE Agreement.
Total savings on the GMS,DP and LTI schemes were estimated at €248.5 million.
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6th Feb 09 - NCPE reports on the cost-effectiveness of ambrisentan (Volibris®) in the treatment of patients with Functional Class II or III pulmonary arterial hypertension.
A summary of the main findings are included in the attached document.
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