National Centre for Pharmacoeconomics

National Centre for

NCPE Ireland

Cysteamine bitartrate delayed-release (Procysbi®)

Procysbi® for the treatment of proven nephropathic cystinosis.

NCPE Assessment Process Completed
Rapid review received 01/12/2015
Rapid review completed 15/12/2015
Rapid Review Outcome Full pharmacoeconomic assessment recommended at the submitted price
Full pharmacoeconomic assessment commissioned by HSE 23/12/2015
Pre-submission consultation with applicant 22/05/2017
Submission received from applicant 13/07/2017
Preliminary review sent to applicant 22/08/2017
NCPE assessment re-commenced 29/08/2017
Applicant factual accuracy check 17/10/2017
NCPE assessment re-commenced 15/11/2017
NCPE assessment completed 15/11/2017
NCPE assessment outcome Reimbursement not recommended at the submitted price


The HSE has approved reimbursement following confidential price negotiations; July 2019