National Centre for Pharmacoeconomics

National Centre for

NCPE Ireland

Dacomitinib (Vizimpro®)

Dacomitinib (Vizimpro®) is indicated as monotherapy, for the first-line treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR)-activating mutations.


NCPE Assessment Process Complete
Rapid review commissioned 01/04/2019
Rapid review completed 13/05/2019
Rapid Review outcome A full HTA is recommended to assess the clinical effectiveness and cost effectiveness of dacomitinib compared with the current standard of care, on the basis of the proposed price relative to currently available therapies


The HSE has approved reimbursement following confidential price negotiations (November 2019).