National Centre for Pharmacoeconomics

National Centre for

NCPE Ireland

Neratinib is indicated for the extended adjuvant treatment of adults with early-stage hormone receptor-positive, HER2-overexpressed/amplified breast cancer and who completed adjuvant trastuzumab-based therapy less than one year ago.


NCPE Assessment Process Complete
Rapid review commissioned 18/12/2019
Rapid review completed 30/01/2020
Rapid Review outcome A full HTA is recommended to assess the clinical effectiveness and cost effectiveness of neratinib compared with the current standard of care.