National Centre for Pharmacoeconomics

National Centre for

NCPE Ireland

Tofacitinib is indicated for the treatment of adult patients with moderately to severely active UC who have had an inadequate response, lost response, or were intolerant to either conventional therapy (i.e. corticosteroids, azathioprine, 6-mercaptopurine) or a biologic agent (i.e. TNF inhibitor).


NCPE Assessment Process Complete
Rapid review commissioned 16/07/2018
Rapid review completed 18/09/2018
Rapid Review outcome A full HTA is recommended to assess the clinical effectiveness and cost effectiveness of tofacitinib compared with the current standard of care, on the basis of the proposed price relative to currently available therapies.