Trastuzumab Deruxtecan (Enhertu®). HTA ID: 25039

Assessment Status Rapid Review Complete
HTA ID 25039
Drug Trastuzumab Deruxtecan
Brand Enhertu®
Indication Trastuzumab deruxtecan (Enhertu®) is indicated as monotherapy for the treatment of adult patients with unresectable or metastatic hormone receptor (HR)-positive, HER2-low or HER2-ultralow breast cancer who have received at least one endocrine therapy in the metastatic setting and who are not considered suitable for endocrine therapy as the next line of treatment.
Assessment Process
Rapid review commissioned 13/06/2025
Rapid review completed 14/07/2025
Rapid review outcome A full HTA is recommended to assess the clinical effectiveness and cost effectiveness of trastuzumab deruxtecan compared with the current standard of care.