Acalabrutinib (Calquence®) for MCL. HTA ID: 25041

Assessment Status Rapid Review Complete
HTA ID 25041
Drug Acalabrutinib
Brand Calquence®
Indication Acalabrutinib (Calquence®) in combination with bendamustine and rituximab is indicated for the treatment of adult patients with previously untreated mantle cell lymphoma (MCL) who are not eligible for autologous stem cell transplant (ASCT).
Assessment Process
Rapid review commissioned 30/06/2025
Rapid review completed 21/07/2025
Rapid review outcome A full HTA is recommended to assess the clinical effectiveness and cost effectiveness of acalabrutinib + BR compared with the current standard of care.