Selpercatinib (Retsevmo®) for advanced RET fusion-positive non-small cell lung cancer. HTA ID: 25035

Assessment Status Rapid Review Complete
HTA ID 25035
Drug Selpercatinib
Brand Retsevmo®
Indication Selpercatinib is indicated as monotherapy for the treatment of adult patients with advanced RET fusion-positive non-small cell lung cancer not previously treated with a RET inhibitor.
Assessment Process
Rapid review commissioned 22/08/2025
Rapid review completed 10/10/2025
Rapid review outcome A full HTA is not recommended. The NCPE recommends that selpercatinib for this indication not be considered for reimbursement at the submitted price.

Next steps: The NCPE Assessment Report and recommendation, will be considered by the HSE when making their decision on reimbursement, while also having regard to the criteria specified in the Health (Pricing and Supply of Medical Goods) Act 2013.

 

Further information on this process may be found here.

 

Further information on the status of this decision may be found here.