| Assessment Status | NCPE Assessment Process Complete |
| HTA ID | 25052 |
| Drug | Blinatumomab |
| Brand | Blincyto® |
| Indication | Blinatumomab (Blincyto®) is indicated as monotherapy as part of consolidation therapy for the treatment of adult patients with newly diagnosed Philadelphia chromosome negative CD19 positive B-cell precursor acute lymphoblastic leukaemia. |
| Assessment Process | |
| Rapid review commissioned | 20/08/2025 |
| Rapid review completed | 12/09/2025 |
| Rapid review outcome | A full HTA is recommended to assess the clinical effectiveness and cost effectiveness of blinatumomab for this indication compared with the current standard of care. |
| Full HTA commissioned by the HSE | 01/10/2025 |
| Pre-submission consultation with Applicant | 05/11/2025 |
| Full submission received from Applicant | 07/04/2026 |
| Preliminary review sent to Applicant | 30/06/2026 |
| NCPE assessment re-commenced | 31/07/2026 |
| Factual accuracy sent to Applicant | 08/09/2026 |
| NCPE assessment re-commenced | 16/09/2026 |
| NCPE assessment completed | 24/09/2026 |
| NCPE assessment outcome | The NCPE recommends that blinatumomab monotherapy, as part of consolidation therapy for the treatment of adult patients with newly diagnosed Philadelphia chromosome-negative CD19-positive BCP-ALL who are MRD-negative, be considered for reimbursement if cost-effectiveness can be improved relative to existing treatments*. |
*Next steps: The NCPE Assessment Report and recommendation and Patient Organisation submission, will be considered by the HSE when making their decision on reimbursement, while also having regard to the criteria specified in the Health Pricing and Supply of Medical Goods Act 2013.
Further information on this process may be found here.
Please see the HSE Pricing and Reimbursement Tracker for any updates on the reimbursement status of this drug.
HSE Pricing and Reimbursement Tracker