Carfilzomib (Kyprolis®) in combination with dexamethasone (CAR+DEX).

Assessment Status Rapid Review complete
Drug Carfilzomib (in combination with dexamethasone)
Brand Kyprolis®
Indication For the treatment of adult patients with multiple myeloma who have received at least one prior therapy
Assessment Process
Rapid review commissioned 11/02/2019
Rapid review completed 19/03/2019
Rapid review outcome A full HTA is recommended to assess the clinical effectiveness and cost effectiveness of carfilzomib in combination with dexamethasone compared with the current standard of care, on the basis of the proposed price relative to currently available therapies.

The HSE has approved reimbursement following confidential price negotiations; October 2020