The NCPE believe that, at the submitted price, eribulin (Halaven®) is not cost effective for the treatment of patients with locally advanced breast cancer or metastatic breast cancer who have progressed after at least two chemotherapeutic regimens for advanced disease.

For the treatment of adult patients with BRAF V600 mutation-positive unresectable or metastatic melanoma. The NCPE believe that, at the submitted price, vemurafenib (Zelboraf®) is not cost effective for this indication.

As the manufacturer is unable to demonstrate the cost-effectiveness of fampridine we are unable to recommend reimbursement

The NCPE believe that apixaban is cost effective for this indication

Following a price revision we now consider rivaroxaban a cost-effective therapy for this indication.

The NCPE believe that, at the submitted price, Abiraterone Acetate (Zytiga®) is not cost-effective for the treatment of patients with metastatic castration-resistant prostate cancer (mCRPC)

We believe that at the submitted price, Ozurdex® cannot be considered cost-effective therapy for the treatment of macular oedema following retinal vein occlusion.

The NCPE believe that, at the submitted price, cabazitaxel is not cost-effective for the treatment of patients with mHRPC previously treated with a docetaxel-containing treatment regimen.

Full Pharmacoeconomic Evaluation Recommended

Economic evaluation of a universal childhood pneumococcal conjugate vaccination strategy in Ireland PCV13 is the most cost-effective option if the analysis is based on a serotype distribution reflecting 2011 data. download document