National Centre for Pharmacoeconomics

National Centre for

NCPE Ireland

Ravulizumab (Ultomiris®) HTA ID: 20036

Ravulizumab is indicated in the treatment of patients with a body weight of 10 kg or above with atypical haemolytic uremic syndrome (aHUS) who are complement inhibitor treatment-naïve, or have received eculizumab for at least 3 months and have evidence of response to eculizumab.


NCPE Assessment Process Complete
Rapid review commissioned 24/07/2020
Rapid review completed 21/08/2020
Rapid Review outcome A full HTA is recommended to assess the clinical effectiveness and cost effectiveness of ravulizumab (Ultomiris®) compared with the current standard of care, on the basis of the proposed price relative to currently available therapies.
Full pharmacoeconomic assessment commissioned by the HSE 27/08/2020
Pre-submission consultation with Applicant 28/06/2021
Current Status Awaiting HTA submission from Applicant