| 23012 |
Acalabrutinib |
Calquence® |
Indicated as monotherapy or in combination with obinutuzumab for the treatment of adult patients with previously untreated chronic lymphocytic leukaemia (CLL). The Applicant is seeking reimbursement in a subgroup of the licensed population: as monotherapy for previously untreated CLL without 17P deletion or TP53 mutation, in adult patients unsuitable for chemoimmunotherapy and venetoclax in combination with obinutuzumab. |
Company no longer intend to submit a full HTA dossier |
11th March 2024 |
 |
| 22030 |
Dapagliflozin |
Forxiga® |
Indicated in adults for the treatment of symptomatic chronic heart failure with reduced ejection fraction. |
Rapid review complete |
14th March 2024 |
|
| 23065 |
Dapagliflozin |
Forxiga® |
Dapagliflozin (Forxiga®) is indicated in adults for the treatment of symptomatic chronic heart failure with left ventricular ejection fraction >40%. |
Rapid Review Complete |
14th March 2024 |
|
| 23030 |
Deucravacitinib |
Sotyktu® |
Deucravacitinib is indicated for the treatment of moderate to severe plaque psoriasis in adults who are candidates for systemic therapy. |
Rapid Review Complete |
14th March 2024 |
|
| 23052 |
Doxylamine/pyridoxine |
Cariban® |
Doxylamine/pyridoxine (Cariban®) is indicated for the symptomatic treatment of nausea and vomiting during pregnancy in adults who do not respond to conservative management. |
Rapid Review Complete |
14th March 2024 |
|
| 21063 |
Dupilumab |
Dupixent® |
For adults and adolescents 12 years and older as add-on maintenance treatment for severe asthma with type 2 inflammation characterised by raised blood eosinophils and/or raised fraction of exhaled nitric oxide (FeNO), who are inadequately controlled with high dose inhaled corticosteroids (ICS) plus another medicinal product for maintenance. |
Rapid review complete |
14th March 2024 |
|
| 22024 |
Enfortumab vedotin |
Padcev® |
As monotherapy for the treatment of adult patients with locally advanced or metastatic urothelial cancer (la/mUC) who have previously received a platinum-containing chemotherapy and a programmed death receptor-1 or programmed death-ligand 1 inhibitor |
NCPE Assessment Process Complete |
14th March 2024 |
|
| 23007 |
Foslevodopa/foscarbidopa |
Produodopa® |
Foslevodopa/foscarbidopa (Produodopa®) is indicated for the treatment of advanced levodopa-responsive Parkinson's disease with severe motor fluctuations and hyperkinesia or dyskinesia when available combinations of Parkinson medicinal products have not given satisfactory results. |
Rapid Review Complete |
14th March 2024 |
|
| - |
Lumacaftor/ivacaftor |
Orkambi® |
For the treatment of cystic fibrosis (CF) in patients aged 12 years and older who are homozygous for the F508del mutation in the CFTR gene. |
Assessment process complete |
14th March 2024 |
|
| 22069 |
Maribavir |
Livtencity® |
For the treatment of cytomegalovirus (CMV) infection and/or disease that are refractory (with or without resistance) to one or more prior therapies, including ganciclovir, valganciclovir, cidofovir or foscarnet in adult patients who have undergone a haematopoietic stem cell transplant or solid organ transplant. |
Rapid Review Complete |
14th March 2024 |
|
| 22070 |
Oral Azacitidine |
Onureg® |
For maintenance treatment in adult patients with acute myeloid leukaemia who achieved complete remission or complete remission with incomplete blood count recovery following induction therapy with or without consolidation treatment and who are not candidates for, including those who choose not to proceed to, haematopoietic stem cell transplantation. |
Rapid Review Complete |
14th March 2024 |
|
| 21066 |
Osimertinib |
Tagrisso® |
For adjuvant treatment after complete tumour resection in adult patients with stage IB-IIIA Non-Small Cell Lung Cancer whose tumour has epidermal growth factor receptor exon 19 deletions or exon 21 (L858R) substitution mutations. |
NCPE Assessment Process Complete |
14th March 2024 |
|
| 22042 |
Pembrolizumab |
Keytruda® |
Is indicated for the adjuvant treatment of adults and adolescent (≥12 years) with stage IIB or IIC melanoma following complete resection. |
NCPE Assessment Process Complete |
10th March 2024 |
|
| 23017 |
Relugolix |
Orgovyx® |
Indicated for the treatment of adult patients with advanced hormone-sensitive prostate cancer. |
Rapid Review Complete |
14th March 2024 |
|
