Base Case

Analysis conducted using the set of preferred methods most appropriate for the decision-maker

Bayesian Method

A branch of statistics that uses prior information based on subjective opinion and objective evidence, such as the results of previous research, for estimation and inference


Bias is any distorting influence that makes the results of a study an inaccurate reflection of the true situation

Birch bark extract (Filsuvez®). HTA ID: 23069

Assessment Status Awaiting full HTA submission from Applicant
HTA ID 23069
Drug Birch bark extract
Brand Filsuvez®
Indication Treatment of partial thickness wounds associated with dystrophic and junctional epidermolysis bullosa (EB) in patients 6 months and older.
Assessment Process
Rapid review commissioned 10/11/2023
Rapid review completed 08/12/2023
Rapid review outcome A full HTA is recommended to assess the clinical effectiveness and cost effectiveness of birch bark extract compared with the current standard of care.
Full pharmacoeconomic assessment commissioned by HSE 18/12/2023
Pre-submission consultation with Applicant 23/04/2024


When patients, investigators, researchers and/or assessors are kept unaware of the allocation of treatments (investigational agent or control) to participants in a study

Budget Impact Analysis

Estimates the financial consequences of adoption and diffusion of a new health-care intervention within a specific health-care setting or system context given inevitable resource constraints.