Entrectinib (Rozlytrek®). HTA ID: 22055

Assessment Status Rapid review complete
HTA ID 22055
Drug Entrectinib
Brand Rozlytrek®
Indication As monotherapy is indicated for the treatment of adult and paediatric patients 12 years of age and older with solid tumours expressing a neurotrophic tyrosine receptor kinase (NTRK) gene fusion, who have a disease that is locally advanced, metastatic or where surgical resection is likely to result in severe morbidity, and who have not received a prior NTRK inhibitor and who have no satisfactory treatment options
Assessment Process
Rapid review commissioned 09/08/2022
Rapid review completed 29/09/2022
Rapid review outcome A full HTA is recommended to assess the clinical effectiveness and cost effectiveness of entrectinib compared with the current standard of care, on the basis of the proposed price relative to currently available therapies