| 25039 |
Trastuzumab Deruxtecan |
Enhertu® |
Trastuzumab deruxtecan (Enhertu®) is indicated as monotherapy for the treatment of adult patients with unresectable or metastatic hormone receptor (HR)-positive, HER2-low or HER2-ultralow breast cancer who have received at least one endocrine therapy in the metastatic setting and who are not considered suitable for endocrine therapy as the next line of treatment. |
Full HTA submission received from Applicant |
17th April 2026 |
 |
| 25049 |
Trastuzumab deruxtecan |
Enhertu® |
Trastuzumab deruxtecan as monotherapy is indicated for the treatment of adult patients with advanced HER2-positive gastric or gastroesophageal junction (GEJ) adenocarcinoma who have received a prior trastuzumab-based regimen. |
Awaiting full HTA submission from Applicant |
25th February 2026 |
|
| - |
Trastuzumab emtansine |
Kadcyla® |
For the treatment of adult patients with HER2-positive, unresectable locally advanced or metastatic breast cancer who previously received trastuzumab and taxane, separately or in combination. |
Assessment process complete |
1st July 2014 |
|
| 20002 |
Trastuzumab emtansine |
Kadcyla® |
As a single agent, for the adjuvant treatment of adults with HER2-positive, early breast cancer who have residual invasive disease, in the breast and/or lymph nodes, after neoadjuvant taxane-based and HER2-targeted therapy. |
Assessment process complete |
12th March 2021 |
|
| 23073 |
Tremelimumab |
Imjudo® |
Tremelimumab (Imjudo®) in combination with durvalumab (Imfinzi®) is indicated for the first line treatment of adults with advanced or unresectable hepatocellular carcinoma. |
NCPE Assessment Process Complete |
11th July 2025 |
|
| - |
Trientine Tetrahydrochloride (TETA 4HCL) |
Cuprior® |
For the treatment of Wilson’s disease in adults and children ≥ five years intolerant to D-penicillamine therapy. |
Rapid Review Complete |
9th October 2019 |
|
| - |
Trifluridine/tipiracil |
Lonsurf® |
For the treatment of adult patients with metastatic colorectal cancer who have been previously treated with, or are not considered candidates for, available therapies including fluoropyrimidine-, oxaliplatin- and irinotecan-based chemotherapies, anti-VEGF agents, and anti-EGFR agents. |
Rapid Review Complete |
13th July 2016 |
|
| 22011 |
Trifluridine/tipiracil |
Lonsurf® |
As monotherapy for the treatment of adult patients with metastatic gastric cancer including adenocarcinoma of the gastroesophageal junction, who have been previously treated with at least two prior systemic treatment regimens for advanced disease. |
Rapid Review Complete |
15th March 2022 |
|
| 22058 |
Tucatinib |
Tukysa® |
In combination with trastuzumab and capecitabine for the treatment of adult patients with HER2-positive locally advanced or metastatic breast cancer wo have received at least two prior anti-HER2 treatment regimens. |
NCPE Assessment Process Complete |
25th September 2025 |
|
